Precision vWF Immunoprecipitation & Immunoblotting ELISA Kit, accurate hemostasis analysis and von Willebrand disease research.

Precision vWF Immunoprecipitation & Immunoblotting ELISA Kit

Precision vWF Immunoprecipitation & Immunoblotting ELISA Kit, accurate hemostasis analysis and von Willebrand disease research. ELISA Kit for Quantitative measurement of VWF propeptide (protocol included) in vascular disorders, von Willebrand disease and acquired von Willebrand syndrome. VWF immunoprecipitation and immunoblotting, Studies on von Willebrand factor synthesis.

Article number MW1939
Product group Quantitative measurement of VWF propeptide
Technique ELISA Functional Assay (FN)

General information

Disclaimer: Purchaser acknowledges that the product is experimental in nature and provided WITHOUT WARRANTY
OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE OR ANYOTHER WARRANTY, EXPRESS OR IMPLIED.
The Seller would not be responsible for injury or damages resulting from the use or misuse of any of its products.

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vWF Immunoprecipitation & Immunoblotting: ELISA Kit Applications


Von Willebrand factor (VWF) immunoprecipitation and immunoblotting are two techniques used to study VWF, a protein that plays a crucial role in the process of blood clotting.

It is primarily involved in platelet aggregation, which is the process by which platelets stick together to form a clot. vWF is also important for maintaining the integrity of blood vessels. Deficiency or dysfunction of vWF can lead to a bleeding disorder called von Willebrand disease. There are three types of von Willebrand disease (VWD) ,Type 1,2,3. Type 1 is the mildest form and type 3 is the severe one. Symptoms of VWD can include excessive bleeding from cuts or injuries, heavy or prolonged menstrual periods, and spontaneous nosebleeds or bleeding from the gums. Treatment of VWD typically involves replacement therapy with vWF concentrates.

Reliable Detection with vWF-specific ELISA Kits

Accuracy is paramount in laboratory diagnostics, and our vWF-specific ELISA kits are designed to meet this need with unmatched reliability. These kits are optimized for the detection and analysis of von Willebrand factor, a pivotal player in hemostasis and thrombosis research. By leveraging the specificity of our ELISA kits, researchers can confidently quantify the vWF propeptide levels in their samples, leading to a deeper understanding of von Willebrand disease and other related vascular conditions. Our commitment to quality ensures that every kit delivers consistent results, providing a solid foundation for both clinical and investigative applications.

Technical information

Accuracy in vWF ELISA Testing

VWF is a glycoprotein involved in hemostasis. The preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder.

Alternate Names:

von Willebrand factor

Gene ID:

7450

UniProt ID:

P04275

Specificity:

Human VWF propeptide, as established by functional, immunoprecipitation and immunoblotting studies

Host:

Mouse

Immunogen:

Pro-VWFgly763

Components: Mouse Anti-Propeptide VWF Monoclonal Antibody Pair Capture/Coating Antibody: CS-MW1939-A (clone CLB-Pro 35) Detection Antibody: CS-MW1939-B (clone CLB-Pro 14.3) - HRP-conjugated
Formulation:  CS-MW1939-A (CLB-Pro 35) is dissolved in 20 mM TRIS, 150 mM NaCl, pH 8.0, 0.001% Merthiolate. CS-MW1939-B HRP-conjugated (CLB-Pro 14.3) is dissolved in 20 mM TRIS, 150 mM NaCl, pH 8.0, 1% BSA, 0.001% Merthiolate.
Concentration: Each antibody is 100-fold concentrated. Total volume is 375 µL for each antibody, sufficient for 3 microtiter plates of 96 tests.
Applications:  ELISA, Functional Studies
Application Notes:  Quantitative measurement of VWF propeptide by ELISA (protocol attached) in vascular disorders, von Willebrand disease and acquired von Willebrand syndrome. Studies on von Willebrand factor synthesis. The optimal concentration should be determined by the user for each specific application.
Storage & Stability:  For long-term storage, freeze in working aliquots at -20 °C. Avoid repeated freeze-thaw cycles.


NOT FOR HUMAN USE. FOR RESEARCH ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC USE

White label product.

Uncover the Mysteries of Von Willebrand Factor with Immunoprecipitation and Immunoblotting

Storage and stability

hemostasis analysis

For long-term storage, freeze in working aliquots at -20 °C.
Avoid repeated freeze-thaw cycles.

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