Products from Essange Reagents / Sanquin

Celebrating Over a Decade of Partnership: Advancing Global Health with Essange/ Sanquin Reagents

We are proud to celebrate over 10 years of collaboration with Essange Reagents solidifying our role as their global distributor and preferred partner. This enduring partnership highlights our commitment to advancing biomedical research and diagnostics through the provision of high-quality immune reagents and innovative solutions.

In October 2022, Sanquin Reagents B.V. became independent and continues under a new tradename: Essange Reagents. Essange Reagents co-works with the units Sanquin Research & Labservices and Sanquin Diagnostic Services B.V.

Essange Reagents’ IgG subclass reagents and most CD monoclonal antibodies, used for diagnostic purposes, have been extensively documented and meet the requirements of the IVDD. The Technical Documentation includes detailed product descriptions, stability data, validations, and descriptions of the quality management system.

Our extensive network and logistical capabilities facilitate the seamless delivery of these premium immune reagents. As a preferred partner, we maintain the highest standards of service and support, fostering trust and reliability among our clients.

Essange Reagents are produced in accordance with ISO 13485 and EN ISO 13485 certifications, underscoring their commitment to quality and regulatory compliance.

Through this long-standing collaboration, we aim to accelerate innovation in life sciences and healthcare, empowering researchers to make groundbreaking discoveries. We look forward to continuing our fruitful partnership with Essange Reagents and Sanquin, working together to improve global health and well-being.

laboratory products
Essange Reagents Sanquin

Immune reagents

M1895 PeliClass human IgG Subclass Plus kit

This kit is designed to quickly and accurately measure different types of human IgG antibodies (IgG1, IgG2, IgG3, and IgG4).

M1891 PeliClass sheep anti human IgG1

Backed by meticulous fractionation, our sheep anti-human IgG subclass sera eliminate unwanted subclasses.

M1892 PeliClass sheep anti human IgG2

The nephelometric assessment of IgG2 concentrations in serum is grounded in a targeted interaction with a monospecific anti-IgG subclass antiserum.

M1893 PeliClass latex sheep anti human IgG3

This kit ensures specificity through refined fractionated sheep anti-human IgG subclass sera, absorbed to eliminate unwanted subclasses.

M1894 PeliClass latex sheep anti human IgG4

IgG4 quantification relies on a turbidimetric approach with latex reagents coated in highly avid anti-IgG subclass antibodies, enhancing sensitivity.

M1896 PeliClass human IgG subclass Plus calibrator set

Calibrator set in combination with M8191/92/ 93/ 94/ 95, liquid human sera with assigned values for each human IgG subclass.

M1897 PeliClass human IgG subclass Plus control 1

A liquid human serum intended for use as a control sample in the quantitative determination of the four human IgG subclasses (M1895).

M1898 PeliClass human IgG subclass Plus control 2

A liquid human serum intended as a control sample for the quantitative determination of the four human IgG subclasses (M1895).

M9261 Anti-Daratumumab antibody

Anti-Daratumumab is a chimeric rabbit/human antibody targeting Daratumumab and binding free Daratumumab in samples.

M9261 Anti-Guselkumab antibody

Anti-Guselkumab is a chimeric rabbit/mouse antibody targeting Guselkumab and binding free Guselkumab in samples.

M9263 Anti-Dupilumab antibody

Anti-Dupilumab is a chimeric rabbit/mouse antibody targeting Dupilumab and binding free Dupilumab in samples.

M9264 Anti-Tocilizumab antibody

Anti-Tocilizumab is a chimeric rabbit/mouse antibody targeting Tocilizumab and binding free Tocilizumab in samples.

M9265 Anti-Vedolizumab antibody

Anti-Tocilizumab is a chimeric rabbit/mouse antibody targeting Tocilizumab and binding free Tocilizumab in samples.

M9121 PeliClass Anti-human IgG1 (MH161-1)

Specific detection of human IgG1 using the MH161-1 clone, optimized for indirect assays such as ELISA to measure IgG1 levels in human samples.

M9174 PeliCluster Anti-Granzyme B (GB11)

Specific detection of Granzyme B in cytotoxic T lymphocytes and NK cells, optimized for flow cytometry. The monoclonal antibody (Clone GB11) ensures high specificity for apoptosis and cell death studies.

M1538 PeliCluster CD41, 1mL

This monoclonal mouse antibody is a useful marker for studies of megakaryoblasts and megakaryoblastic leukaemias.

MW1939 Antibody pair anti-human VWF propeptid

Quantitative Analysis Kit for VWF Propeptide in Vascular Disorders, von Willebrand Disease, and Acquired von Willebrand Syndrome.

M2032 Streptavidin poly‐HRP, 1mL

Streptavidin conjugated to Poly-Horseradish Peroxidase enhances detection in biochemical assays through its strong affinity for biotin, useful in research and diagnostics.

M9316 PeliPairTM human cytokine Elisa reagent set

PeliPair: Precision ELISA Reagents for Human IL‐6 antibodies for ELISA, Cytokine Quantification in Cell Culture Supernatants.

M1940 HPE buffer, 55mL

This antibody pair contains the monoclonal antibodies CLB-PRO 35 and HRP-labeled CLB-PRO 14.3 for easy and specific detection of VWF propeptide.

M9161 HPE buffer, 1L

The 1 liter version of the M1940. for easy and specific detection of VWF propeptide.

M1981 Toolset 2 for VWF pp antibody pair

ELISA kit for measuring VWF:PP in plasma, aiding in VWF deficiency characterization. Includes all essential reagents.

M2018 PeliKine Human IL-6 ELISA Rapid Set A

Validated ELISA kit for precise and rapid detection of IL-6 in MAT supernatants, designed to support pyrogen testing in compliance with European Pharmacopoeia standards.

M2019 PeliKine Human IL-6 ELISA Rapid Set B

Specific detection and quantification of IL-6 in MAT supernatant, optimized for use with ELISA in pyrogen testing according to European Pharmacopoeia guidelines.

M9128 PeliCluster CD28 CLB-CD28/1, 15E8

Specific detection and quantification of CD28 expression on human T-cells and activated B-cells, optimized for use in flow cytometry and fluorescence microscopy to study T-cell activation and co-stimulation mechanisms

M9166 PeliCluster CD3 (CLB-T3/4E;1XE)

Specific detection and quantification of CD3 expression on human T-lymphocytes, optimized for use in flow cytometry and functional studies to investigate T-cell activation and proliferation mechanisms.

M9171 PeliCluster Granzyme B (CLB-ID5)

Detection of human Granzyme B with clone CLB-GB11, optimized for flow cytometry and immunohistochemistry, targeting a key protease in immune cell-mediated apoptosis.

M9173 PeliCluster Granzyme B (GB10)

Detection of human Granzyme B with clone GB10, optimised for ELISA and immunohistochemistry, targeting a crucial serine protease involved in immune cell-mediated apoptosis.

M9050 PeliCluster ANCA (CLB-12.8)

Detection of c-ANCA with clone CLB-12.8, optimised for flow cytometry and immunohistochemistry, enabling precise identification of this autoantibody associated with vasculitis and related autoimmune conditions.

M9089 PeliCluster MPO (CLB-MPO-1/1; 7.17)

Detection of MPO with clone CLB-MPO-1/1 (7.17), optimised for flow cytometry and immunohistochemistry, targeting myeloperoxidase in neutrophils and monocytes.

M9139 PeliCluster CD36 (CLB-IVC7)

Specific detection and quantification of CD36 expression on human cells, optimized for use in flow cytometry and research studies to investigate its role in cellular adhesion, lipid metabolism, and scavenger receptor activity.

M9087 PeliCluster CD16 (CLB-FcR gran/1; 5D2)

Detection and quantification of CD16 on NK cells, neutrophils, monocytes, and macrophages, optimized for flow cytometry and immune response studies.

M9146 PeliCluster CD66e (CLB-gran/10; IH4Fc)

Detection and quantification of CD66e (CEACAM5) using the CLB-gran/10 (IH4Fc) clone, optimized for flow cytometry and studies on cell adhesion and tumor biology.

Essange Reagents Antibody Table

Reference number Clone Antigen Isotype Buffer Specificity
M9050 CLB-12.8 ANCA IgG1 20 mM TRIS, 150 mM NaCI 80-100% positive with granulocytes
M9117 CLB-T1/1; 1C12 CD5 IgG1 20 mM Borat buffer + 150 mM NaCI 54-80% positive reaction with Lymphocytes
M9087 CLB-FcR gran/1; 5D2 CD16 IgG2a PBS + 0.1% NaN3 90-100% positive reaction with granulocytes
M9127 CLB-LFA1/1; 54 CD18 IgG1 20 mM TRIS, 150 mM NaCI 85-100% positive reaction with the lymphocytes
M9169 CLB-CD27/1; 9F4 CD27 IgG2a 20 mM TRIS, 150 mM NaCI 60% - 85% positive with lymphocytes
M9128 CLB-CD28/1; 15E8 CD28 IgG1 20 mM TRIS, 150 mM NaCI 50-75% positive reaction on PHA-stimulated lymphocytes
M9139 CLB-IVC7 CD36 IgG1 20 mM TRIS, 150 mM NaCI or 90-100% positive reaction with monocytes
M9049 CLB-gran/12; 435 CD63 IgG1 20 mM TRIS, 150 mM NaCI 70-100% positive reaction with activated platelets
M9146 CLB-gran/10; IH4Fc CD66acde IgG1 20 mM TRIS, 150 mM NaCI 95 to 100% positive with activated granulocytes
M9158 CLB-Ery1; AME-1 CD235a IgG1 20 mM TRIS, 150 mM NaCI 95 -100% positive with erythrocytes
M9196 GB12 Granzyme B IgG1 20 mM TRIS, 150 mM NaCI 8-25% positive with lymphocytes (cytoplasmatic)
M9105 MH16-1 IgG IgG1, kappa 20 mM TRIS, 150 mM NaCI Negative with lgG deficient serum
M9179 TNFα-7 TNF-alfa IgG1 20 mM TRIS, 150 mM NaCI Suitable as coat in TNF specific ELISA’s
M9089 CLB-MPO-1/1; 7.17 MPO IgG2a 20 mM TRIS, 150 mM NaCI 80 - 100% positive reaction with cytoplasmatic granulocytes
M9174 GB11 Granzyme B IgG1 20 mM TRIS, 150 mM NaCI 8-25% positive with lymphocytes (cytoplasmatic)
M9199 CLB-GA28 Granzyme A IgG1 20 mM TRIS, 150 mM NaCI (+0.09% (w/v) NaN3 as preservative) x
M9171 GB7 Granzyme B IgG2a 20 mM TRIS, 150 mM NaCI x
M9173 GB10 Granzyme B IgG1 20 mM TRIS, 150 mM NaCI x
M9261 4D1 Daratumumab IgG1, kappa PBS + 0.01% NaN3 x
M9262 8C3 Guselkumab IgG1, kappa PBS + 0.01% NaN3 x
M9263 1G11 Dupilumab IgG1, kappa PBS + 0.01% NaN3 x
M9264 7E9 Tocilizumab IgG1, kappa PBS + 0.01% NaN3 x
M9265 1C7 Vedolizumab IgG1, kappa PBS + 0.01% NaN3 x
M9023 CLB-T11.1/1 CD2 * * *
M9238 CLB-HIK27 CD2 * * *
M9243 CLB-thromb/8; 4E1 CD9 * * *
M9152 CLB-CALLA/1; 4F9 CD10 * * *
M9106 CLB-gran/11; 5D7 CD16b * * *
M9004 CLB-B4/1; 11G1 CD19 * * *
M9118 NKI-IH4 CD20 * * *
M9245 CLB-4D3; 5D1 CD21 * * *
M9005 CLB-B-Ly/1 CD22 * * *
M9246 CLB-gran-B-ly/1; IB5 CD24 * * *
M9178 CLB-22C3 CD26 * * *
M9145 CLB-MD33.6 CD33 * * *
M9096 CLB-MD34.2 CD34 * * *
M9107 CLB-ID5 CD38 * * *
M9119 CLB-tromb/7; 6C9 CD42b * * *
M9248 NKI-P2; P2 CD44 * * *
M9073 CLB-T200/1; 15D9 CD45 * * *
M9102 NKI-SAM-1 CD49e * * *
M9047 NKI-GoH3 CD49f * * *
M9236 NKI-M9 CD51 * * *
M9120 CLB-tromb/1; C17 CD61 * * *
M9206 CLB-2F2 CD70 * * *
M9153 FAS18 CD95 * * *
M9162 CLB-1D4 CD138 * * *
M9231 CLB-203; 5A497 Control IgG1 * * *
M9232 713 Control IgG2a * * *
M9200 CLB-GA29 Granzyme A * * *
M9204 CLB-GA6 Granzyme A * * *
M9159 MD5 IFN-gamma * * *
M9104 MH14-1 IgA * * *
M9177 MH25-1 IgE * * *
M9182 MH15-1 IgM * * *
M9209 IL-1β-8 IL-1-beta * * *
M9113 CLB-IL-4-1 IL-4 * * *
M9114 CLB-IL-4-5 IL-4 * * *
M9090 CLB-IL-6.16 IL-6 * * *
M9184 MH29-2 L-chain Lambda * * *
M9166 CLB-T3/4.E; 1XE CD3 IgE 50-85% positive with human Lymphocytes
M9125 CLB-T4/1; 10A12 CD4
* is not yet finalised as product, can be developed upon needs